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The role of Keap1-Nrf2 signaling pathway in the treatment of respiratory diseases and the research progress on targeted drugs

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Lungs are exposed to external oxidants from the environment as in harmful particles and smog. causing oxidative stress in the lungs and consequently respiratory ailment. The NF-E2-related factor 2 (Nrf2) is the one with transcriptional regulatory function. while its related protein Kelch-like ECH-associated protein 1 (Keap1) inhibits Nrf2 activity. https://www.roneverhart.com/HP-15-fc0093dx-15-6-FHD-Laptop-AMD-Ryzen-5-7520U-2-8-GHz-AMD-Radeon-16GB-LPDDR5-256GB-SSD-Windows-11-Home-S-8F1A6UA/
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